Wixi does support some commandline options:
Wixi 1.05 (c) 2006-2008 k.remmelzwaal@planet.nl
Options:
-r <dir> --repository=<dir> (repository containing wiki's)
-w <wiki> --wiki=<wiki> (start with a specific wiki)
-g <geom> --geometry=<geom> (window width and height, default=850x550)
-v --viewmode (view only mode)
--navpanel=<left|off|right> (disable or align category/search panel, default=left)
--iconsize=<small|large> (select the size for icons, default=large (gtk))
wixi.py -r /mnt/cdrom/
wixi --navpanel=off
wixi --viewmode